Title: Effects of pre-fed and post fed amoxicillin-clavulanate 625 mg on gastrointestinal motility symptoms.

Biography:

Dr. Anuraag B. Choudhary is an Associate Professor, Department of Oral Medicine & Radiology. He has completed his Case series based research at VSPM Dental College, Nagpur, Maharashtra.

Abstract

Objective: To investigate effects of pre fed (fasting) and post fed (non- fasting) amoxicillin-clavulanate 625 mg on gastrointestinal motility symptoms.

Study Design: The Amoxicillin clavulanate 625 mg was prescribed to patients to evaluate pre fed and post fed effect on gastrointestinal motility symptoms. This study was a double – blinded Randomized Controlled Trial (RCT) and was carried out on 60 subjects divided into two groups: {1st group – 30 individuals in pre fed (fasting) group and 2nd group – 30 individuals in post fed (post- prandial) group}.

Results: Number of patients who shows gastrointestinal motility symptoms in of both groups were evaluated and compared with each other. Gastrointestinal motility symptoms were found in 5 patients from 1st group (pre fed) and 18 patients from 2nd group (post fed).

Conclusion: This study concluded that gastrointestinal motility symptoms were observed less in patients who were prescribed with pre fed (fasting) Amoxicillin- clavulanate 625 mg than patients who were prescribed with post fed (non-fasting) Amoxicillin-clavulanate 625mg.