Dr. Maria Bertha Romo Almanza, completed her postgraduate degree in Neonatology at the National Institute of Perinatology, in Mexico City, completing this specialty at 30 years edge (2009), previously she has a specialty in Pediatrics at the Children's Hospital in Saltillo Coahuila, currently she is Chief in charge in Neonatology Inensive Care Unit at the Guadalupe Victoria Maternity and Child Hospital of Atizapan de Zaragoza since 5 years ago . Previously she was Chief in charge in NICU at Star Médica Luna Parc Cuautitlan Izcalli , where he continues his private practice. Instructor Neonatal CPR , member from ANEM , APROLAM She has published articles in international Journals, and have participation like speaker in diferents international conferences.
Abstract
As you know in recent years there has been an increase in the critically ill newborns’ survival, thanks to advances in the Neonatology, bringing with it, the development of multiple pathologies, with the consequent increase in the risk of presenting perinatal infections, specially in the group corresponding to prematurity, the incidence and severity of infections in the newborn being well documented, which is largely due to immaturity in both the cellular and humoral response. Reporting a limited functional capacity of all components, in addition to observing quantitative and qualitative deficiencies in the immune system´s cellular components so it is important to develop safe strategies such as supplementation with micronutrients, which allow improving the immune response in the body, of these children. Two decades ago, it was documented that Vitamin D3 in addition to having a regulatory function in the homeostasis of calcium and phosphorus has a relevant role in the modulation of the immune response, Its action is exerted through the union with its nuclear receptor and intervenes activating transcription factors The Receptor is present in cells of different tissues and of the immune system, such as dendritic cells, macrophages and T lymphocytes.