Title: The myocardial blood flow and coronary flow reserve using SPECT technique

Biography:

Wong Siong Sung is a Consultant Cardiologist at National University Heart Centre Singapore. He is subspecialized in Nuclear Cardiology, Cardiovascular CT and Cardiovascular MRI. He is one of the pioneers in the establishment of the quantification of myocardial blood flow and coronary flow reserve using SPECT imaging technique in Singapore. He did his Advanced Fellowship Training in Nuclear Cardiology at Royal Brompton Hospital and Harefield Hospital, London, United Kingdom and University College Hospital, London, UK. He has interpreted numerous numbers of cases in the field of nuclear cardiology, cardiovascular CT and cardiovascular MRI. He always has great interest to integrate multi-modality imaging to provide better care to the patients.

Abstract

Single-photon emission computed tomography (SPECT) imaging is an established imaging technique to assess for myocardial ischemia, infarction and viability. However, the technique still has its weakness where balanced myocardial ischemia in the setting of multi-vessels coronary artery disease and micro-vascular dysfunction can be missed. Recently, there is revolutionary development in the field of the nuclear cardiology whereby the quantification of myocardial blood flow and coronary flow reserve with an innovative Tc-99m sestamibi dynamic single-photon emission computed tomography (SPECT) method had been established using solid state gamma camera. The quantification of the myocardial blood flow and coronary flow reserve are used to enhance its ability to detect balanced myocardial ischemia and micro-vascular dysfunction. This development is shown to be comparable with the conventional coronary flow reserve quantification using positron emission tomography (PET) technique at much cheaper cost and more readily available. The detection of multi-vessels coronary artery disease and micro-vascular dysfunction is shown to be of great importance to patient’s management and carry a significant prognostic value. I will present cases of myocardial blood flow and coronary flow reserve done in National University Hospital Singapore.