International Conference on

Nanotechnology

Scientific Program

Pankaj Singla

Pankaj Singla

Manchester Metropolitan University, UK

Title: Temperature induced solubilization of hydrophobic active pharmaceutical ingredient lamoterigine in different pluronics - A detailed solubilization, SANS, DLS, HTM, in-vitro release and microscopy study

Biography:

Pankaj Singla is pursuing PhD under the supervision of Prof. R. K. Mahajan from GNDU, Amritsar India and currently he is working as Visiting PhD scholar under the supervision of Dr. Marloes Peeters in Manchester Metropolitan University, Manchester UK. His area of interest is to deliver the hydrophobic drugs viz. anticancer drugs, antiepileptic drugs via Polymeric based nanoparicles

Abstract

Pluronic (Tri–block copolymers) play an important role in pharmaceutical performance to increase the solubility and bioavailability of hydrophobic drugs. These micelles often lack stability, exhibit unsatisfactory drug loading capacity, or have broad size distribution this work aims to solve this issue by studying the solubilization of hydrophobic drugs in different pluronic micelles at variable temperature. Herein, a series of five pluronic micelles viz. P84, P85, F127, F108 and F68 have been select for study solubilization of hydrophobic drug Lamotrigine (LAM) at different temperatures i.e. 370C, 470C and 570C using UV-Visible spectroscopy. 

  • Nanotechnology
  • Nano Medicine
  • Bio Nanotechnology
  • Green Nanotechnology
  • Food Nanotechnology
  • Nano Engineering
  • Nano Electronics
  • Nano Composites
  • Nano Fabrications
  • Nano Mechanics
  • Nano Toxicology
  • Forensic Nanotechnology
  • Nano Photonics
Pankaj Singla

Pankaj Singla

Manchester Metropolitan University, UK

Title: Temperature induced solubilization of hydrophobic active pharmaceutical ingredient lamoterigine in different pluronics - A detailed solubilization, SANS, DLS, HTM, in-vitro release and microscopy study

Biography:

Pankaj Singla is pursuing PhD under the supervision of Prof. R. K. Mahajan from GNDU, Amritsar India and currently he is working as Visiting PhD scholar under the supervision of Dr. Marloes Peeters in Manchester Metropolitan University, Manchester UK. His area of interest is to deliver the hydrophobic drugs viz. anticancer drugs, antiepileptic drugs via Polymeric based nanoparicles

Abstract

Pluronic (Tri–block copolymers) play an important role in pharmaceutical performance to increase the solubility and bioavailability of hydrophobic drugs. These micelles often lack stability, exhibit unsatisfactory drug loading capacity, or have broad size distribution this work aims to solve this issue by studying the solubilization of hydrophobic drugs in different pluronic micelles at variable temperature. Herein, a series of five pluronic micelles viz. P84, P85, F127, F108 and F68 have been select for study solubilization of hydrophobic drug Lamotrigine (LAM) at different temperatures i.e. 370C, 470C and 570C using UV-Visible spectroscopy. 

  • Nanotechnology
  • Nano Medicine
  • Bio Nanotechnology
  • Green Nanotechnology
  • Food Nanotechnology
  • Nano Engineering
  • Nano Electronics
  • Nano Composites
  • Nano Fabrications
  • Nano Mechanics
  • Nano Toxicology
  • Forensic Nanotechnology
  • Nano Photonics