International Microfluidics Webinar
Scientific Program
Petr Solich
Charles University, Czech Republic
Title: Micro-flow analysis with monolithic columns
Biography:
Petr Solich is the Vice-dean for strategic development and European funds, Professor, Head of the Department of Analytical Chemistry, Group Leader of Analytical Chemistry Group (ACG). He Guarrantee of OPVVV project Establishment of Specialized Team for Advanced Research on Separation Science” STARSS, Guarrantee of OPVVV project „Efficiency and Safety improvement of Current Drugs and Nutraceuticals: advanced methods – new challenge“ - EFSA-CDN.
Abstract
Miniaturization in flow analysis can be done by several ways, one of them is Sequential Injection Chromatography (SIC), which use monolithic columns for separation processes and presently is already becoming well-established analytical technique.
Monolithic materials proved their role both as sorbents for solid phase extraction and chromatographic separation. These methods profit from large active surface (mesopores) and highly porous structure (macropores) of the monoliths. Although available commercially, significant benefit arises from ease of their preparation in laboratory. Numerous approaches can be used for preparation of monoliths leading to materials varying in active surface, porosity, chemistries, polymer properties, and size. This flexibility results in extraction and separation sorbents including formats such as pipette tip for solid phase extraction (SPE), micro-column SPE, well-plate SPE, and HPLC analytical and capillary columns that are finding applications in manual, semi-automated, and on-line methods. Typical target samples include complex environmental and biological matrixes, as well as all kinds of inorganic and organic analytes including biomolecules. A broad range of micro-flow analysis methods have already been developed using monoliths .
Fundaments, overview, trends, and perspectives of monoliths in micro-flow analysis will be discussed. An overview of several recent applications of the use of monolithic columns in micro-flow techniques will also be pointed out .
- Applications of Microfluidics & Lab-on-a-Chip
- Droplet-based, Digital, Centrifugal Microfluidics
- Point-of-Care & Biosensors
- Wearables & Mobile Diagnostics
- Micro-chemistry and Micro-systems
- Nano-channel, Micro-channel and Mini-channel
- Bio-fabrication & Bio-manufacturing
- Optofluidics, Plasmonic and Bioimaging Devices
- Acoustic Droplet Ejection
- Tissues-on-a-Chips and 3D Cell Culture Systems
- Drug Discovery in Microfluidics
- Microfluidics Simulation
