Multicomponent reactions (MCR) have gained popularity over the past few decades in the world of chemistry.  (MCR) is a chemical reaction where 3 or more compounds react together to produce a one product. The concept of privileged medicinal scaffolds was originally introduced by Merck researchers, during the course of their work on benzodiazepines, recently acting as a guiding principle in modern drug discovery.  Privileged scaffolds generally consist of a rigid ring structure such as a heterocyclic ring. 3,5-Dicyanopyridines are an important privileged heterocyclic scaffold. In our research, we explored the methodology to synthesize 4-aryl-6-sulfanylpyridine derivatives by MCR. The derivatives of 4-phenylpyridine are reported to show excellent biological activities.  A three-component reaction of 4-anisaldehyde, malonitrile, and NaSH produced a very important intermediate-2-amino-3,5-dicyano-6-mercapto-4-(4-methoxyphenyl)-pyridine. Alkylation reaction on sulfur of this intermediate will result in various 3,5-dicyano-6-sulfanyl pyridine products as desired. All products were characterized by 1H NMR and 13C NMR spectroscopy.