Ilyes Safir, worked two year as a scientific assistant at the Federal Institute for Materials Research and Testing (BAM) in Berlin-Germany, afterward, he went to the University of Geneva- Switzerland to pursue his PhD until the age of 33 years. Now he is teaching mathematics and physics in private high School.
Abstract
In the following is described the combination of straight biochemical and organic routes to graft nucleotide sequences to a chitosan backbone. The resulting chitosan-g-ssDNA hybrid self-assembles into submicrometer size structures in dilute aqueous solution as assessed by atomic force and electron microscopy imaging. The hypothesis of self-assembly driven by chemical incompatibility between the amphiphilic chitosan and nucleic acid grafts is supported further by stability of the self-assembly against ionic strength and pH variations.
