Providing a comprehensive understanding of diabetes mellitus, covering its epidemiology, etiology, pathophysiology, and diagnostic criteria to lay the foundation for subsequent discussions on management and complications.
Type 1 Diabetes, Type 2 Diabetes, Gestational Diabetes, Diabetes Mellitus
Exploring the multifaceted complications arising from diabetes, including microvascular and macro vascular complications, alongside strategies for prevention, early detection, and optimal management with Foot Complications, Gastroparesis, Hypoglycemia
Health Care professionals can diagnose diabetes, prediabetes, and gestational diabetes through blood tests. The blood tests show if your blood glucose, is too high or low. Type 1 diabetes seen in children and young adults. Because type 1 diabetes can run in families, even if they don’t have symptoms. Experts suggests testing children between the ages of 10 and 18 who are overweight or obese and have at least two other risk factors for developing diabetes.
Delving into the principles, modalities, and advancements in insulin replacement therapy for diabetes management, encompassing insulin types, administration techniques, dose titration, and strategies to optimize glycemic control while minimizing hypoglycemia and other adverse effects
Obesity occurs when a man's muscle mass exceeds his fat mass to the point where it threatens his health. A man is considered corpulent if his body weight is at least 20% more than it should be. If your Body Mass Index (BMI) is between 25 and 29.9, you are considered overweight. If your BMI is 30 or over, you are considered overweight. Diabetes mellitus is a chronic, long-term disease that affects your body's ability to utilise the energy available in food. Type 1 diabetes, type 2 diabetes, and gestational diabetes are the three types of diabetes to be aware of. Something similar can be found in a wide variety of diabetes mellitus. Normally, your body converts the sugars and carbs you consume into a single sugar known as glucose.
Diabetic patients' wound healing slows down due to a variety of causes, including diabetes. High glucose levels (When your glucose level is greater than normal, it prevents nutrients and oxygen from reaching cells, preventing your immune system from functioning properly and, in the long run, causing aggravation in the body's cells.) (Neuropathy) is the damage caused to nerve cells as a result of persistently elevated glucose levels. This could result in a loss of sensation in the affected areas. Diabetic individuals' hands and feet are commonly affected. When it occurs, one will be unable to feel wounds when they happen. This is one noteworthy motivation behind why foot wounds have a tendency to be more typical in individuals with diabetes.
A diagnosis of prediabetes should serve as a wake-up call to patients to undertake lifestyle adjustments that will help them avoid full-blown diabetes and cardiovascular disease (CVD). We know that having diabetes raises the risk of acquiring cardiovascular disease, therefore we wanted to see what the absolute risk or probability of developing heart disease was for those with blood sugar levels that were only slightly higher than pre-diabetic. A fasting blood sugar level of 100 to 125 mg/dL (5.6 to 6.9 mmol/L) indicates prediabetes, but a fasting blood sugar level of less than 100 mg/dL (5.6 mmol/L) is considered normal. The diagnostic threshold for diabetes is 126 mg/dL (7 mmol/L) or higher.
Delving into the latest advancements in basic and translational research focused on elucidating the physiology, pathophysiology, and therapeutic targets of endocrine glands, spanning from molecular mechanisms to clinical applications.
Types of Glands:
Scrutinizing the diagnosis, staging, treatment modalities, and multidisciplinary management of endocrine-related malignancies, encompassing thyroid, adrenal, pituitary, and neuroendocrine tumors, and addressing emerging therapeutic approaches and challenges.Thyroid Cancer, Adrenal Tumors, Pituitary Tumors, Parathyroid Cancer, Neuroendocrine Tumors, Endocrine Pancreatic Tumors, Surgical Interventions
Endocrine diseases influence the body's ability to digest certain nutrients and vitamins, whereas metabolic disorders affect the body's ability to over- or under-produce certain hormones. Hypothyroidism, congenital adrenal hyperplasia, parathyroid gland diseases, diabetes mellitus, adrenal gland diseases (including Cushing's syndrome and Addison's disease), and ovarian dysfunction (including polycystic ovary syndrome) are among the endocrine disorders. The study of hormone processes and neuroendocrine systems that influence or govern behaviour is known as behavioural endocrinology. Endocrinology is a broad field that impacts not just our endocrine system but also our skin, implying that dermatology is involved indirectly.
In the differential diagnosis of menstrual irregularities and infertility, diabetes mellitus Type 1 and Type 2 should be examined. Diabetic women's reproductive periods may be shortened as a result of delayed menarche and premature menopause. Diabetes has been linked to menstruation disorders such as oligomenorrhea and secondary amenorrhea during the reproductive years. Better glycemic control and the prevention of diabetic complications were discovered to improve these abnormalities and bring fertility rates closer to those reported in the general population. Women with persistent menstrual abnormalities despite adequate treatment need to be approached by broader evaluation, which will include the examination of the hypothalamic-pituitary-ovarian axis and the hormonal status, presence of autoimmune thyroid disease and antiovarian autoantibodies, and hyperandrogenism.
Providing insights into the spectrum of thyroid disorders, including hypothyroidism, hyperthyroidism, thyroid nodules, and thyroid cancer, exploring diagnostic modalities, treatment options, and considerations for personalized management.
Examining the bidirectional relationship between mental health disorders and endocrine conditions, addressing the impact of hormonal imbalances on mood, cognition, and behavior, and integrating mental health considerations into comprehensive endocrine care.
Addressing the unique aspects of diagnosing, treating, and managing endocrine disorders in pediatric populations, encompassing growth disorders, puberty-related issues, congenital adrenal hyperplasia, diabetes, and other hormone-related conditions like Growth Disorders, Diabetes in Children, Genetic Syndromes. Exploring the intricate interplay between the endocrine system and the central nervous system, elucidating neuroendocrine pathways, and their roles in regulating homeostasis, stress responses, mood, behavior, and reproductive function.
Osteoporosis is a global age-related health concern that affects both male and female senior people. It slowly deteriorates the microstructure of bone, especially at trabecular locations like vertebrae, ribs, and hips, leading to fragility fractures, pain, and disability. Diabetes mellitus (DM), particularly type 1 DM, leads to and/or aggravates bone loss in osteoporotic patients, despite the fact that osteoporosis is generally associated with ageing and oestrogen shortage. This subject spotlight article covers DM-induced osteoporosis and DM/osteoporosis comorbidity, as well as changes in bone metabolism and hormones that regulate bone formation in diabetic patients, such as insulin, insulin-like growth factor-1, and angiogenesis. Also covered are the cellular and molecular processes of DM-related bone loss. This knowledge lays the groundwork for a better understanding of diabetes complications as well as the development of early osteoporosis screening and prevention in diabetic patients.
Investigating the impact of dietary factors and interventions on endocrine health, including nutritional approaches to diabetes management, weight loss, metabolic syndrome, and other hormone-related conditions, and exploring dietary guidelines and lifestyle modifications.
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