Title: Therapeutic effects of combinatorial biologics (mRNA and allogenic MSCs) with a spinal cord stimulation system on a patient with spinal cord section. Dr Joel

Biography:

Dr. Dr. Osorio is an innovative businessman with a distinct entrepreneurial mindset concentrated adding value on areas of Biotechnology
(mRNA), Reprogramming & Regenerative Medicine for translational use in humans and a variety of clinical applications aimed for both the
private and the public health sectors. Dr. Osorio is the Founder, President, and CEO of RegenerAge Clinic and RegenerAge Beauty initiatives
for transnational implementations. Vice President and International Clinical Developer for Bioquark, Inc. Executive Vice President: Chairman of
the WAMS Americas Division, member of the WAMS Executive Council (WAMS Executive Board), a member of the WAMS Education &
Training Board (ETB), a member of the WAMS Editorial Board, an Honorary Member of the Academy Faculty FWAMS, an Honorary Fellow of
the Academy & is also a Senior Partner at WAMS, The World Academy of Medical Sciences.

Abstract

Bioquantine® a mRNA extract from Xenopus laevis frog oocytes
(purified from intra- and extra-oocyte liquid phases of electroporated
oocytes), showed potential as a treatment for a wide range of conditions
in animal models, including Spinal Cord Injury (SCI) and Traumatic
Brain Injuries (TBI) among others. The current study observed
beneficial changes with Bioquantine® administration in a patient with a
severe SCI. Pluripotent stem cells have therapeutic and regenerative
potential in clinical situations CNS disorders. One method of
reprogramming somatic cells into pluripotent stem cells is to expose
them to extracts prepared from Xenopus laevis oocytes. Due to ethical
reasons and legal restrictions we selected a No Option patient, deciding
to include in our protocol the RestoreSensor SureScan to complete it.
Based on the electrical stimulation for rehabilitation and regeneration
after spinal cord injury published by Hamid and MacEwan, we designed
an improved delivery method for the in-situ application of MSCs and
Bioquantine® in combination with the RestoreSensor® SureScan®.
To the present day the patient who suffered a complete section of spinal
cord at T12-L1 shows an improvement in sensitivity, strength in striated
muscle and smooth muscle connection, 14 months after the first
Bioquantine® and MSCs treatment and 9 months after the placement
of RestoreSensor® at the level of the lesion, showing an evident
improvement on his therapy of physical rehabilitation (legs movement)
on crawling forward and backwards and standing on his feet for the first
time and showing a progressively important functionality on both limbs.