Webinar on

RNA and Genomics

May 28, 2021

Webinar on RNA and Genomics

Theme: Exploring the unexpected diversity of RNA molecules in Genomic World

RNA – Genomics Webinar welcomes every one of the participants, professors, associates, delegates and speakers from across the globe throughout the world to attend this webinar on May 28th, 2021.  During this time of crisis webinar gives you the opportunity to connect and share knowledge and experience about a given topic. Webinar helps to connect different people and gives you the right amount of exposure required during this time of crisis. A genome is the complete set of DNA (or RNA in RNA viruses) of an organism. It is sufficient to build and maintain that organism. Each nucleated cell in the body contains this same set of genetic material. Another type of nucleic acid is RNA, or ribonucleic acid. RNA translates DNA into proteins, and is the genetic material of some prokaryotes and viruses. Unlike DNA, RNA only has one strand and the sugar in RNA is ribose sugar molecules, not deoxyribose in DNA.This Webinar hopes that the Professor, Researchers, Students and Business Beasts that are joining would give their ideas and thoughts on this topic which would help in the practical improvement and would discover some advances in the field of RNA-Genomics.

 

Sessions Summary - 

  • Introduction To Genomics -

    Genomics is the study of whole genomes of organisms, and incorporates elements from genetics. Genomics uses a combination of recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the structure and function of genomes. It differs from ‘classical genetics’ in that it considers an organism’s full complement of hereditary material, rather than one gene or one gene product at a time. Moreover, genomics focuses on interactions between loci and alleles within the genome and other interactions such as epistasis, pleiotropic and heterocyst.
     
  • Structure of RNA -

    RNA, abbreviation of ribonucleic acid, complex compound of high molecular weight that functions in cellular protein synthesis and replaces DNA (deoxyribonucleic acid) as a carrier of genetic codes in some viruses. RNA consists of ribose nucleotides (nitrogenous bases appended to a ribose sugar) attached by phosphodiester bonds, forming strands of varying lengths. The nitrogenous bases in RNA are adenine, guanine, cytosine, and uracil, which replace thymine in DNA.
     
  • Genome Composition , Organization and Expression -

    The Human Genome Initiative is a worldwide research effort that has the goal of analyzing the sequence of human DNA and determining the location of all human genes. Begun in 1990, the U.S. Human Genome project was originally planned to last 15 years but now is projected to be complete in 13 years. This project was started to find the 80,000 - 100,000 human genes and to determine the sequence of the 3 - billion chemical bases that make up human DNA. The information generated by the human genome project is expected to be the source book for biomedical fields, including those such as developmental biology and neurobiology, where scientists are just beginning to understand the underlying molecular mechanisms. The human genome project is expected to immensely benefit medical science. It will help us to understand and eventually treat many of the more than 4000 genetic diseases that afflict mankind, as well as the many multifunctional diseases in which genetic predisposition plays an important role. New technologies emanating from the genome project will also find application in other fields such as agriculture and the environmental sciences.
     
  • Role of RNA is Genome Stability -

    The genome is constantly exposed to both endogenous and exogenous sources of damage, with DNA double-strand breaks (DSBs) being among the most harmful DNA lesions. In consequence, there are an ample variety of factors involved in ensuring the accurate and timely repair of breaks throughout the cell cycle. Recent evidence supports that the context in which breaks occur can somehow affect the outcome of the repair mechanisms. In particular, the potential impact by RNA molecules is emerging to be a new fascinating and controversial field of study. Because transcription is an essential process that constantly generates RNA transcripts for protein synthesis, RNA interference pathways, as well as non-coding RNAs, which can renewal with the DNA template to form DNA-RNA hybrids, it makes these transcribed regions a hot bed for DNA DSBs.
     
  • Importance of RNA in Genome -

    RNA, in one form or another, touches nearly everything in a cell. RNA carries out a broad range of functions, from translating genetic information into the molecular machines and structures of the cell to regulating the activity of genes during development, cellular differentiation, and changing environments.RNA is a unique polymer. Like DNA, it can bind with great specificity to either DNA or RNA through complementary base pairing. It can also bind specific proteins or small molecules, and, remarkably, RNA can catalyze chemical reactions, including joining amino acids proteins. All the RNA in cells is themselves copies of DNA sequences contained in the genes of a cell's chromosomes. Genes those are copied—"transcribed"—into the instructions for making individual proteins are often referred to as "coding genes." The genes that produce RNAs used for other purposes are therefore called "noncoding RNA" genes.

 

  • Introduction To Genomics
  • Structure of RNA
  • Genome Composition , Organization and Expression
  • Role of RNA is Genome Stability
  • Importance of RNA in Genome