Diabetes is a group of metabolic disorders associated with chronic hyperglycemia in the blood that occurs due to a defect in the insulin secretion or insulin function or both. Type 1 diabetes is an autoimmune disease that is associated with destruction of pancreatic beta cells in producing of insulin. Type 2 diabetes causes an increase in blood glucose due to decreased insulin secretion and function. Diabetes mellitus is linked with cardiovascular diseases and kidney and liver failures. Although the proper treatment of diabetes includes insulin injection continuously to maintain blood glucose level, but nowadays, the researchers following some adjunctive natural healings for diabetes. Dry extract of milk thistle seeds has 1-4 % silymarin that reduces blood glucose by acting on glucose-6-phosphatase and inhibiting gluconeogenesis. However, silymarin reduces insulin secretion without causing high blood sugar, and this effect can be helpful in treatment of hyperinsulinemia in type 2 diabetes. It is proved that anethole (the active ingredient in anise) can control blood sugar levels and improve the function of the pancreas cells. Tribulus terrestris plant may lead to delayed glucose uptake and reduce blood glucose by inhibiting of alpha glucosidase and suppression of glucose transfer from gastric to small intestine and inhibition the transfer of glucose across the small intestine and prevent hepatic gluconeogenesis. The licorice extract has anti-diabetic and anti-inflammatory effects that help to lower blood sugar, prevent insulin resistance and type 2 diabetes. Phenolic compounds in plant extracts such as Moringa may be to some extent responsible for the anti-diabetic and antioxidant properties. Some other effective herbs on type 2 diabetes are including cinnamon, okra, clove, fenugreek, ginger, garlic and cumin. Camel milk contains insulin like proteins, which does not form coagulum in the acidic condition of stomach, and may be an effective alternative for insulin to treat type 1 and 2 and gestational diabetes. Camel milk may reduce required insulin dose about 30–35% in type 1 diabetes patients. Lactoferrin of camel milk has immune- modulatory effects on pancreas beta-cells and reduces required insulin doses in diabetes 1 and 2 patients. Obviously, camel milk effects on regulating of blood glucose are including; effect on insulin receptor function, signaling and glucose transport in the insulin-sensitive tissues, effect on the growth and activity of the pancreatic beta-cells in insulin secretion and negative modulation on the glucagon receptor. It is concluded, camel milk can be helpful for type 2 diabetes and reduce the required insulin and blood glucose. It appears that more scientific studies are needed to confirm the effectiveness of some natural herbs and camel milk on diabetes cases.

Several studies demonstrate the potential benefits of camel milk in many health issues and diseases with significant anti-diabetic and anti-inflammatory properties.
However, limited data are present in the literature on the thermal effect on camel milk biological activities. Thus, the aim of this study was to evaluate the changes in anti-inflammatory and alpha amylase activities and insulin content of camel milk after thermal treatment.
Methods: Camel milk were collected from the experimental herd of the Livestock and Wildlife laboratory (Arid Lands Institute, Medenine, Tunisia). Insulin ELISA Kit was procured from Demeditec (Germany). The anti-inflammatory activity and the α-amylase inhibitory activities was tested in vitro on the different heat-treated camel milk. 
Results: The anti-inflammatory activity of camel milk was affected by the heat treatment at high temperature. The inhibition results of alpha-amylase as indicator for antidiabetic activity was significantly lower in boiled milk compared to fresh milk (Control). 
There was also a significant difference in the insulin content in heat-treated groups when compared with the control group (fresh milk). In fact, the concentration of insulin in milk decreases by increasing the temperature of the heat treatment. 
Conclusion: The pasteurization at a temperature of 63°C of camel milk could be the suitable alternative to preserve the anti-inflammatory activity, the antidiabetic properties and the insulin content of camel milk for a longer time. 

Background: Mangroves are the world’s productive ecosystem. They are adapted to high salinity, wide range of temperature and pressure with enormous microbial diversity that are exploited for the production of novel bioactive compounds. Among the other microbial activity. Actinomycetes play a high prominent role in producing bioactive components since the conditions of halophillic environment are extremely varied compared to terrestrial environment that retards the growth of life threatening multi drug resistant pathogens and their antibacterial agents are highly sourceful to many biomedical properties acts as antitumor agents, anticancer agents, immunosuppressive agents, antioxidants and enzyme inhibitors.
Materials and Methods: Actinomycetes are heterogenous group of Gram positive bacteria with excellent G+C contents in their DNA. The present study was aimed to isolate the Actinomycetes from different regions of mangrove sediments of selected media. Isolated organisms were further screened based on diversified nature morphologically, preliminary characterization and their antagonistic activity was enhanced by bioactive metabolites obtained from Phosphate buffered intracellular extraction.
Results and Conclusion:
Isolated actinomycetes strains are extensively different and are grouped based on their colony morphology, Physiological, Biochemical and Cultural characterization. Majorty of the strains sustained to the growth of high pH and temperature they also shown positive response to Biochemical analysis. Based on preliminary and secondary screening selected results were notified that the potent actinomycetes strains shown significant inhibition against Multidrug resistant ATCC Pathogenic bacterial cells, hence the Purpose of this study are relevant to many Biomedical applications which can be applicable to pharmaceuticals, Industries and Agro based Research.