Webinar on
Cancer Research
August 25, 2021
Scientific Program
Keynote Session:
Title: The perioperative window presents a long overlooked but important opportunity to prevent relapses in breast and other cancers
Biography:
Michael Retsky received PhD in experimental physics from University of Chicago in 1974. While working at Hewlett-Packard in Colorado Springs in 1982, a friend started an informal cancer research project since his wife was being treated for cancer. Over the next years, Retsky made a career change into cancer research. His first paper in oncology (Cancer Research 1984) predicted that tumour growth included periods of dormancy. He eventually became Prof of Biology at Univ of Colorado and later on staff of Judah Folk man at Harvard. He is now Hon Assoc Prof at University College London. Retsky was diagnosed with Stage IIIc colon cancer in 1994. Based on his knowledge of tumour kinetics he used low-dose, long-term chemotherapy instead of maximum tolerated chemotherapy. This became the first use of metronomic chemotherapy.
Abstract:
My colleagues and I have been studying an anomalous relapse pattern in breast cancer. This project started in 1993 when data from Italy and UK showed that 50 to 80% of all relapses in patients treated only with surgery occurred in an early wave of relapses in the first 3 years post-surgery. We proposed a reasonable explanation. It appears that the surgery to remove a primary tumour causes systemic inflammation for a week. During that time, dormant single malignant cells and avascular deposits escape from dormancy and appear as relapses within 3 years. The multi-national authors of our reports include medical oncologists, surgeons, anaesthesiologists, physicists, and other scientists from several fields. A potential solution seems to exist based on our analysis. That therapy is the common inexpensive analgesic ketorolac administered as IV at the time of surgery and perhaps as oral drug for a few days after surgery. We edited a book and published a number of papers including one recently (1). Two animal models support our findings (2, 3). Another paper suggests a way to prevent some late relapses (4) and a second retrospective clinical trial was reported (5).
Title: The Purpose of Temperature of Fever in Covid -19
Biography:
K. M. Yacob is a practicing physician in the field of healthcare in the state of Kerala in India for the last 31years and very much interested in basic research. My interest is spread across the fever, inflammation and back pain. I am a writer. I already printed and published nine books on these subjects. I wrote hundreds of articles in various magazines. After scientific studies, we have developed 8000 affirmative cross checking questions. It can explain all queries related to fever.
Abstract:
When the disease made by virus becomes a threat to life or organs blood circulation decreases, Temperature of fever will emerge to increase prevailing blood circulation. And it acts as a protective covering of the body to sustain life.
When blood flow decreases to the brain, the patient becomes fainted-delirious. If we try to decreases the temperature of fever, the blood circulation will further be reduced. Blood circulation never increases without temperature increase. Delirious can never be cured without an increase in blood circulation.
The temperature of fever is not a surplus temperature or it is not to be eliminated from the body. During fever, our body temperature increases like a brooding hen`s increased body temperature.
The actual treatment to fever is to increase blood circulation. Two ways to increase blood circulation. 1. Never allow body temperature to lose 2. Apply heat from outside to the body. When the temperature produced by the body due to fever and heat which we applied on the body combines together, the blood circulation increases.
Then the body will stop to produce heat to increase blood circulation. And the body will get extra heat from outside without any usage of energy.
