Chemotherapy-induced Leukopenia (CIL) is associated with increased mortality and economic burden on patients. This study was conducted to evaluate whether inclusion of green jackfruit flour 30 gms per day along with regular diet of those patients receiving chemotherapy, could prevent CIL. This is a retrospective study conducted among a group of patients undergoing chemotherapy for solid tumors at Renai Medicity Hospital, Palarivattom, Cochin, Kerala, India, since June 2018. The study group comprised of 50 consecutive subjects, who were supplemented with green jackfruit flour diet in their regular diet and further followed up prospectively. The control group was retrospective with 50 subjects prior to June 2018, with no diet supplements. Those who received less than 3 cycles were excluded from either arm. The mean age of the participants in study group and control group were 53.16±11.06 and 56.96±12.16 years respectively. 6 patients, out of 37, in the study group and 20 patients out of 50 in the control group developed CIL. They received 38 and 105 vials of filgrastim respectively. After excluding those cycles in study group patients, where green jackfruit flour was not taken in spite of advice, the mean number of cycles in which CIL developed (P=0.00) and number of vials of filgrastim taken per cycle (P=0.00) were significantly different from control group and no patient in the study group developed CIL. Inclusion of green jackfruit flour as a dietary intervention prevents chemotherapy-induced leukopenia in patients undergoing chemotherapy along with Pegfilgrastim. Avoidance of CIL improves quality of life, reduces the cost of treatment, morbidity prevents ICU stay, mortality, avoids chemotherapy dropouts, prevents postponement of chemo cycles and even the quality of life of treating doctors since management of neutropenia is avoided. When extrapolated on global scale the money saved will be in billions. This will also permit usage of highly effective drugs, whether cytotoxic or immunotherapy, which otherwise are withdrawn due to chemotoxicity, thus enhancing cure rates

Keywords: Jackfruit flour, chemotherapy-induced leukopenia, chemotoxicity, Pegfilgrastim, plant based natural compounds, Health economics, Quality of life.

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Introduction: Malignant ovary tumor is the one of highest mortality rate in gynecology cancer and the induction of this ovary cancer is related to metabolism and exposure to estrogen.

Purpose: to demonstrate that the use of hormones to treat acne is not safe and the possibility of inducing cancer in the ovaries could be one of the reasons to reduce the indication of these medications to treat acne.

Methods: one case report, a 29-years-old women with pain in the abdomen and after doing some laboratorial exams, nothing was found. Only one ultra-sound that revealed an alteration in the right ovary that was bigger than normal and the surgery was scheduled to see what could be. In the surgery, it was done biopsy that revealed malignant tumor in the right ovary. The patient was submitted to chemotherapy, radiotherapy and started treatment with acupuncture with apex ear bloodletting and did the chakras ‘energy measurement that revealed that all the chakras were in the lowest level of energy. Homeopathy according to the theory Constitutional Homeopathy of the Five Elements based on Traditional Chinese Medicine and crystal-based medications were done to replenish the energy of the chakras’ energy centers. The patient said that she was in taking for ten years hormones to treat acne in the skin. Results: patient need to take out all the womb and part of the ovary due to malignance. She began the use of homeopathies and her energy returned to normalize quickly. Today, she still working at the local secretary and have to put a hair wig due to hair loss when using chemotherapy.

Conclusion: the conclusion of this study is that the use in the hormones can induce the formation of malignant ovary tumor and the correction of the lack of energy diagnosed by radiesthesia procedure, was treated with Chinese dietary counseling, auricular acupuncture and homeopathies medications according to Constitutional Homeopathy of the five Elements based in traditional Chinese medicine and crystal based medications