Title: A Case Report on Osteosarcoma Ex Carcinoma Ex Pleomorphic Adenoma of the Maxillary Alveolar Ridge

Biography:

James Daniel Corpuz is a 2^nd year resident in Otolaryngology Department of Rizal Medical Center, Pasig City, Philippines. He studied Doctor of Medicine at University of Manila. He took BS Human Ecology in University of the Phillippines Los Baños, Laguna, Phillippines

Abstract

This case report highlights the diagnostic dilemma in a case of osteosarcoma of the maxillary alveolar ridge and the importance of accurate histopathologic diagnosis for appropriate course of management. This is a case of a 19-year male who had a 2-month history of rapidly enlarging maxillary alveolar ridge mass. Excision biopsy was done with histopathologic diagnosis of pleomorphic adenoma. After a month, the mass recurred hence, a second excision biopsy was done revealing Intracapsular Carcinoma Ex Pleomorphic Adenoma. After a month, the mass again recurred. The patient consulted at our institution. The mass was completely excised with negative margins. Final histopathologic analysis revealed a possibility of osteosarcoma. Immunohistochemical stains (SATB2, S100 and CK) revealed immunomorphologic features consistent with osteosarcoma.

The patient did not consult our tumour clinic; thus, he noted a recurrence of mass on the right alveolar ridge after 3 months. A wide excision of the recurrent mass was done with negative margins. The patient had a delay again in starting chemotherapy, so there was a recurrence 1 month post-operation. The patient eventually started chemotherapy and is on his third cycle of chemotherapy, with a significant decrease in the size of the mass.