Amsterdam is the capital of Netherlands and most swarmed region of the Kingdom. It is known for its artistic heritage, elaborate canal system and narrow houses with gabled facades, legacies of the city’s 17th-century Golden Age. The 17th-century canals of Amsterdam and the 19–20th century Defense Line of Amsterdam are on the UNESCO World Heritage List. Even then, because Amsterdam is surrounded on three sides by large bodies of water, as well as having a significant heat-island effect, nights rarely fall below −5 °C (23 °F), while it could easily be −12 °C (10 °F) in Hilversum, 25 kilometres (16 miles) southeast.

The Top Medical Universities and Institutions are: Erasmus University Rotterdam, University of Amsterdam, Utrecht University, Leiden University, Maastricht University, VU University Amsterdam, Radboud University Nijmegen, University of Groningen, Wageningen University and Research Center, Eindhoven University of Technology, University of Twente.

Amsterdam's main attractions, including its historic canals, the Rijksmuseum, the Van Gogh Museum, the Stedelijk Museum, Royal Palace, Hermitage Amsterdam, West Church, the Anne Frank House, Rembrandt House Museum, Dam Square, the Amsterdam Museum, Maritime Museum, Vondelpark, Bloemenmarkt, Canals of Amsterdam, red-light district, Port of Amsterdam, and its many cannabis coffee shops draw more than 5 million international visitors annually It is also the world's most multicultural city with at least 177 nationalities represented.