Title: Functional cure for HIV

Biography:

Cecilia Ramirez received her master’s degree at the University of Maryland (College Park, USA) and her Ph.D. degree at the Institut Jacques Monod (Paris) from the Université Paris Diderot. She completed her training at Rutgers University (NJ, USA) as a Post-doctoral fellow and joined the French “Centre National de la Recherché Scientifique” (CNRS) in 1996. She is project leader at the Institut Cochin in Paris. She has focused her research work on the study of viruses-host interactions to understand the molecular mechanisms used by viruses to efficiently multiply by borrowing host’s cell machineries and metabolic pathways. Her team recently showed that spironolactone (SP) is a specific inhibitor of HIV Tat-dependent transcription. They continue to evaluate the transcription block by SP in several latent reservoir models to determine the possibility to use of SP to ‘‘block and lock’’ latent reservoirs leading to a functional cure of HIV as a new strategy to control HIV infection.

Abstract

TBA