Ghada Ahmed El hag Mohamed is a Associate Professor of Zoology in King Abdulaziz University, Jeddah, Saudi Arabia.
Abstract
The aim of this study was to investigate the protective effects of fish oil on lead acetate induced testis toxicity rats. Forty male rats were randomly divided into 4 groups, 10 rats in each. Control rats received normal saline, while treated rats received lead acetate (150 mg/kg body weight) three times weekly, lead acetate and fish oil (650 mg/kg body weight/day) and fish oil (650 mg/kg body weight/day) for six weeks by gavage tube.
The results showed an insignificant increase in mean testis weight with highest and lowest testis weight gained was of 3.09±0.31g and 2.82±0.76 g respectively. Testicular histology of rats treated with fish oil revealed slight changes in the uniformity of arrangements of seminiferous tubules.
Data from present study suggests that fish oil have been initiating the positive effects on testicular normal structure in lead acetate treated rats.