Title: Adipocytokines as a risk factor for coronary artery disease and its relationship with obesity

Biography:

Maytham Hussein Tarrad AL-Dualism holds a bachelor’s degree in 2009 from the University of Baghdad College of Medical Technology, Department of Pathological analysis and currently studying MSc in clinical Biochemistry branch research stage in the college of Medicine University of Babylon.

Abstract

Objective: Obese, normal weight patients with coronary artery diseases and obese, normal weight controls, we sought to investigate the association of a set of adipocytokines, including total adiponectin, leptin and plasminogen activator inhibitor-1(PAI-1), with coronary artery diseases events in obese and normal weight.

Design: Case control study; samples of obese and normal weight with and without coronary artery diseases were selected to detect the levels of adipocytokines and proinflammatory mediators.

Subjects: 50 patients with coronary artery disease divided to groups (25 obese) and (25 normal weight) who diagnosed coronary artery disease in cardiac care center (CCU) and 50 healthy men divided to groups (25 obese) and (25 normal weight) with nearly same ages were determined by enzyme-linked immunosorbent assay, spectrophotometer (UV-Vis) and other instruments which provide by biochemistry department in Babylon University/college of medicine.

Measurements: Adiponectin, leptin, plasminogen activator inhibitor-1(PAI--1), insulin resistance, total lipoprotein, HbA1C and BMI.