Misfolded protein can lead to Amyloids which related to many diseases such as Alzheimer's, Parkinson's, Huntington's. Therefore, studying protein structure is vital to develop a treatment. Here, the lysozyme gold nanocluster (Lyz - AuNCs) is used to study protein folding/unfold. The fluorescence intensity of gold nanocluster is study as function of increasing temperate, Urea and Sodium Dodecyl Sulphate (SDS). It is known that Urea and SDS can lead to fold/ unfold the native (Lyz). The effect of temperature on Bovine serum albumin encapsulated gold nanocluster (BSA – AuNCs) has been studied.

Ultra-high cooling performance is a crucial requirement of many thermomechanical systems, such as microelectronic devices, engine cooling systems, nuclear power systems, chemical reactors, and refrigeration systems. Recent experimental results reveal the potential thermal properties of suspended nanometallics in conventional fluids. In this study, the facile synthesis of one-dimensional delafossite CuAlO2 nanowires by microwave hydrothermal treatment was presented. A novel type of nanofluid consisting ofCuAlO2 nanowires suspended in distilled water at various volume fractions (0.0, 0.2, 0.4, and 0.6 wt%) was successfully synthesized using an easily scalable sonication method. The microstructures of as-synthesized CuAlO2 were investigated by adopting X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), and field-emission scanning electron microscopy (FESEM). Furthermore, the thermal conductivity and specific heat capacity of water-loaded nanofluid were measured at different volume fractions and temperatures. The results reveal a significant increase in thermal conductivity with increasing CuAlO2 loading levels and temperatures. The obtained results propound the fact that water-loaded delafossite CuAlO2 nanowires-based nanofluid is a promising candidate for future industrial applications.

Pluronic (Tri–block copolymers) play an important role in pharmaceutical performance to increase the solubility and bioavailability of hydrophobic drugs. These micelles often lack stability, exhibit unsatisfactory drug loading capacity, or have broad size distribution this work aims to solve this issue by studying the solubilization of hydrophobic drugs in different pluronic micelles at variable temperature. Herein, a series of five pluronic micelles viz. P84, P85, F127, F108 and F68 have been select for study solubilization of hydrophobic drug Lamotrigine (LAM) at different temperatures i.e. 370C, 470C and 570C using UV-Visible spectroscopy.

In present study, ultrafine grained plates made of commercially pure aluminium were obtained in the hybrid process. Initially bar-shaped samples with dimensions of 26 x 26 x 130 mm were processed using severe plastic deformation process, namely multi-turn Equal Channel Angular Pressing (mtECAP). Subsequently, the flattening was performed via multi-stage upsetting process using smooth anvils till 3 mm in thickness was achieved. Furthermore, the initial bar was also flattened in order to reveal the differences between all stages of plastic deformation. The microstructural characterization was performed at each stage of processing and consisted of investigation using Transmission Electron Microscope and Electron Backscatter Diffraction on Scanning Electron Microscope. Mechanical properties were evaluated based on tensile tests. Results have proved the significant grain refinement for separate processes (mtECAP, upsetting), however, the lowest grain size with average value below 700 nm and a significant fraction of 80% of high angle grain boundaries was achieved only by implementing the hybrid process [1]. The EBSD map of the latter one is illustrated in Fig. 1. In the case of mechanical properties, apart from significant mechanical strength improvement, low anisotropy of mechanical properties were obtained for sample after the hybrid process.

One of the mandatory components of radical treatment of patients with endometrial cancer is the impact on regional lymph nodes. Nowadays, pelvic lymphadenectomy remains not only therapeutic, but also a diagnostic method in case of predicting the effectiveness of treatment. However, it is important to point out that there are a lot of complications which can occur after dissection of lymph nodes. Lymphorrhea and lymphocele are among the most common postoperative complications of pelvic lymphadenectomy, with a reported incidence of 1% to 50%. Except for the occurrence of undesirable symptoms it can increase the time of drainage standing, which contributes to the delay of further stages of combined treatment.