Pratibha Dogra is an experienced Respiratory & Sleep Physician with experience of working across tertiary care centers doing high end medicine like solid Transplant programs. have been coordinator of major initiatives in the field of sleep like the foundation of South east Asian Academy of Sleep Medicine. I have deep interest in integrating complimentary therapies in in the treatment of Insomnia.
Abstract
Scrub Typhus (ST) is caused by a bacteria c/a Orientia tsutsugamushi and spreads through bites of infected larval mites. It is the most common differential diagnosis for thrombocytopenia. ARDS associated with ST has high morbidity and mortality. Southeast Asia, Indonesia, China, Japan, North India and northern Australia are most commonly affected by it.
AIMS AND OBJECTIVES: To evaluate clinical and demographic presentation of ST and compare its outcome in patients with or without ARDS.
METHODS: 273 patients’ with suspected ST were retrospectively analysed from January 2016 until December 2017. Clinical features, demographics and outcome were evaluated in all patients with ST.
RESULTS: 85 patients (31.13%) were tested positive and all belonged to North India (100%). 60 had no ARDS and 25 had ARDS. All 60 patients without ARDS recovered completely. Among 25 ARDS, 18 patients recovered and 7 patients died.
CONCLUSION: ST is an important differential diagnosis in patients having fever with thrombocytopenia in Northern India. If associated with ARDS, it has higher occurrence morbidity and mortality. Thus, early consideration of ST in patients who have fever and thrombocytopenia belonging to north India should be considered to prevent the complication of ARDS and mortality.