Sumanth NK has completed his PhD from Sri Devaraj Urs Academy of Higher Education and Research, Karnataka, India. He has published few review articles and research articles in reputed journals. He applied for patent for his invention, Quantitative ELISA for SERPINA4/Kallistatin Government of India. He has 12 years of teaching experience in medical and dental colleges and in clinical diagnostic laboratory with hands on experience on automation with internal and external quality control program. He is having research experience in medical and clinical biochemistry with hands on experience on proteomic techniques.
Abstract
Diagnosing the degree of multifactorial liver cirrhosis is crucial for successful management; early diagnosis may reverse cirrhotic liver to normal. Highly invasive liver biopsy is gold standard diagnostic tool. Existing biomarkers for cirrhosis in clinical practice have narrow applicability due to lack of specificity and sensitivity. Proteins expressed from liver entering into circulation reflect degree of liver dysfunction. Technological advancement in proteomic approach may generate numerous biomarker candidates. Prioritization of candidate is prerequisite for further validation in biomarker pipeline. Hence, present study aims to correlate newly
discovered biomarker candidate with serum levels of direct