Different preparations of Cannabis sativa (commonly marijuana and hashish) are widely used mainly for their euphoric effects. Cannabis after alcohol consumption is by far the most commonly used recreational drug in Europe. About 20% of adults in the European Union (aged 15–64 years), over 62 million people, have tried cannabis at least once in their life [1]. Users and lay people believe that marijuana or hashish is safe. Many cases of cardiovascular events have, however, been related to a cannabis consumption [2-4], and cases of acute ischemia or thrombosis even on the ground of normal coronary arteries have been reported.

To examine the effectiveness of canine influenza vaccination to reduce pulmonary lesions in dogs co-challenged with CIV and S. equi subsp. zooepidemicus.In this study, four groups of 7- to 10-week-old, CIV-naive beagles (32 dogs total) were used. One group was vaccinated with CIV vaccine (group 4) and the remaining 3 groups (groups 1, 2 and 3) were not vaccinated. Group 1 was challenged with CIV, group 2 was challenged with S. equi subsp. zooepidemicus and groups 3 and 4 were co-challenged with CIV and S. equi subsp. zooepidemicus.

The vapor phase methanol process, introduced by ICI technology in 1966, and the liquid phase methanol synthesis process (LPMeOHtm) introduced first by ChemSystems, Inc. (now Nexant) in 1975, are seen as the 2 big research/technology advances in the conventional methanol synthesis technology. The success of these 2 processes, both from a scientific and commercial standpoint, primarily is driven by the very superior, almost anomalous, performance of the proprietary Cu/ZnO/Al2O3ICI technical catalyst, and it’s very unique microstructural features, often termed as a “microcrystalline sponge”. The LPMeOHtm process overcomes some of the glaring drawbacks associated with the vapor phase process, viz., highly exothermal nature of methanol synthesis reactions, presence of local reactor hot spots which presents possibility of thermal runaways, and low per-pass CO/H2 conversions.

Attention deficit and hyperactivity disorder in children (excessive mobility, attention and concentration deficit, impulsivity) are important health problems that may affect life quality lifelong. Attention deficit generally take place with dyslexia,  dyscalculia and dysgraphia which are known generally as specific learning difficulty (SLD)  Principal biochemical mechanism underlying attention deficit and hyperactivity disorder might be related with inadequate synthesizing of dopamine and noradrenalin in brain or rapidly catabolism of these molecules. Dopamine, noradrenalin (norepinephrine) and epinephrine (adrenalin) molecules are named generally as catecholamines. Catecholomines are synthesized at suprarenal glands and from tyrosine amino acid at nerve system First and principal control enzyme named as tyrosine hydroxylase catalyses the hydroxylation of tyrosine to DOPA (dihydroxyphenyl alanine). Composed DOPA is decarboxylased by DOPA-decarboxylase enzyme which is a cytoplasmic enzyme to dopamine (dihydroxy phenyletylamine). Dopamine is converted to epinephrine through dopamine beta hydroxylase. Epinephrine composed this way is converted to norepinephrine through COMT (cathecol-o-methyltransferase) [1]. There is no recalling mechanism of cathecolamines released at adrenal medulla. Cathecolamine synthesing cells at adrenal medulla are named as “chromaffin cells” because these cells are stained to reddish-brown color with potassium dichromate. Chromaffin cells are also found in heart, liver, kidneys, gonads and adrenergic neurons of postganglionic sympathetic system and in central nerve system.

The clinicopathologic features of an isolated, primary adenoid cystic carcinoma of the lacrimal gland in a 65-year-old woman are discussed. The patient presented with a painless, slowly growing, anterior orbital mass, which appeared well circumscribed without bony involvement on imaging. Excisional biopsy was performed and histopathological examination revealed the mass to be adenoid cystic carcinoma of the lacrimal gland. The histology of other epithelial lacrimal gland tumors is discussed with a review of the literature. This case highlights the importance of having a wide differential diagnosis when treating orbital neoplasms.

Abstract Background:  PCOS is the most common ovarian factor of female infertility, in low resource countries clomiphene citrate is the most popular drug used for induction of ovulation as its price is affordable for most of patients with least side effects. Objective: Evaluate the effect of phytoestrogen in women receiving induction with clomiphene citrate when given peri ovulatory to oppose antiestrogenic effect of clomiphene citrate. Methodology: Prospective study conducted on 500 patients with PCOD who attended infertility clinic, patients were randomized into 2 groups both groups received traditional CC induction , group (1) 225 patients received phyto-estrogen, starting in the 7th day of the cycle till the day of HCG injection ,group(2) 225 patients received clomiphene citrate only. Endometrial thickness and follicular growth were assessed by transvaginal US. When follicles reached 18 mm, 10,000 IU HCG was administered together with timed intercourse. Both groups were compared as regard cumulative pregnancy rate, ovulation, endometrial thickness and change in hormonal milieu. Results: Midluteal serum progesterone was significantly higher in the study group as compared with the control group (15.93 ±1.8 versus 12.93 ± 1.8); endometrial thickness was also greater in the study group as compared with the control group, (10.3 ± 1.1 versus 8.2 ± 0.9). Ovulation in the three cycles was in favor of study group 82.5% versus 80.4% but not statistically significant. The CPR was significantly higher in the study group than in the control group (34.2% vs. 20.8%. P = 0.1). There were 6 cases of multiple pregnancy in the study group and 4 cases in the control group. Conclusion: Adding phytoestrogen to CC induction improve ovulation and pregnancy rate, it is a good option for patients with PCOS seeking for pregnancy treatment with affordable price and minimal side effects.

The tick genus, Rhipicephalus (Boophilus), is a common hematophagous parasite found feeding on animals. This study examined the extent to which host DNA in a blood meal in Rhipicephalus, can be identified post feeding using a cytochrome b polymerase chain reaction (PCR) assay. Female adult ticks (0.2 and 0.25 grams) were collected from cows and divided into 2 groups, one group was kept alive so as to analyse DNA degradation due to digestion and the other group was euthanized to analyse degradation due to decomposition. Morphological changes of the ticks were tracked and the presence/absence of cow DNA was analysed over time. Live ticks were analysed daily until they died and the dead ticks were analysed up to 290 days post feeding (PF). The ticks’ gut contents were placed on Whatman® filter paper and dried before Chelex® DNA extraction. A 561 base pair region on the cytochrome b gene of the cow mitochondrial DNA was amplified and PCR products were visualized using agarose gel electrophoresis. Cow DNA was detected in the live ticks up to day 23 PF, however, probability of successful detection went down to at least 33% after day 15 PF. The live ticks started dying from day 40 PF and the last one died 52 days PF. Cow DNA was detected with bright bands in the dead ticks from day 1 PF to day 290 PF which is when the last sample was run, so the detection limit of DNA in dead ticks could not be determined. The persistence of host DNA in ticks showed the utility of ticks in forensic investigations. The methods used in this study can be used in forensic acarology to identify the host species of an arthropod when it is found at a crime scene.

In the present research effort is made to make a “difference”. Analysis is done by sophisticated chromatography techniques to find out whether, “Rock Salt solution” very common ingredient for Indian recipes or “vinegar water” as both substances are known for their antitoxin properties and therefore reduces pesticide residue to its maximum from ladies finger, after soaking it for          2-4 hrs rendering it safe for consumption. Qualitative analysis of malathion was done by HPLC method the  retention time of malathion was found to be 2.825±0.3, and in given sample the retention time in water (2.072) and NS (2.559) was found similar to malathion  (2.825) retention  time, which confirm the presence of malathion in given water and NS sample.