Title: Characterize the outer membrane vesicles of Elizabethkingia anophelis under the stress of antibiotics

Biography:

Ming-Hsien Chiang has his expertise in evaluation and passion in improving the nanoparticle and vaccinology. Our research focused on the identification of vaccine candidates against antimicrobial-resistant bacteria via bioinformatic tools and study the host-pathogen interaction in animal models.

Abstract

Antimicrobial-resistant (AMR) bacterial infections, including those caused by Elizabethkingia anophelis (EA), have emerged as a clinical crisis worldwide. With the increased reports of outbreak and its extensive-antibiotic resistant isolates, the treatment of diseases is challenging. Outer membrane vesicles (OMVs) are purposely secreted by Gram-negative bacteria and contain materials derived from their parent bacterium. OMVs specialize and tailor their functions by carrying different components to challenging environments and communicate with other microorganisms or hosts.