Dr.Erol Guclu Gulanber is a clinician scientist, who is an specialist in Veterinarian Surgery and Integrative Medicine. Between 1989 and 2001, he worked as Assistant Professor in the Veterinary Faculty of Istanbul University; department of surgery. In 1992, Dr. Gulanber became the first veterinarian doctor, who went to the People’s Republic of China from Turkey to get acupuncture education from Beijing Agricultural University, Veterinary College, Department of Traditional Chinese Veterinary Medicine. He completed TCVM and acupuncture course and took the certificate. In 1994, he got the title “Doctor Veterinary Medicine” with the doctorate thesis under the heading “Acupuncture and acupunctural applications in veterinary medicine”. This thesis is the first doctorate thesis, which is related to acupuncture in the field of medical sciences in Turkey. Also, Dr. Gülanber is the clinician, who applied acupuncture in veterinary medicine in Turkey, for the first time.
Abstract
This study was performed to evaluate the use of glycerol-preserved equine amniotic membrane as replacement for full-thickness corneal defects in dogs. Eighteen mixed-breed dogs were used. A perilimbal, full-thickness, 5 mm square corneal defect was created surgically, and a donor implant of equine amniotic membrane of the same size and shape sutured in place with 10–0 nylon simple interrupted sutures. Corneal edema was observed near the implant 24 h after surgery, but was absent after 1 week. Granulation tissue and corneal vascularization superficial to the implant were noticed on postoperative day 7, but were absent on day 30. Corneal vascularization persisted until the end of the experiment. There was no fluorescein retention by postoperative day 30. There was slight clearing of the corneal implant by postoperative 30, and slight pigmentation of the donor implant observed at postoperative day 180. An acute inflammatory process as well as fibroblasts were present at early postoperative stages. At postoperative day 60 there was no inflammatory cellular infiltrate, but fibroblasts and fibrosis were present. Corneal architecture was restored at the end of the experiment, with a layering of the epithelium–stroma–debris of amniotic membrane–stroma–endothelium present, and pigmentation and vascularization present in the deep layers of the cornea. Although vascularization indicated some degree of graft rejection, the clinical and histological evidence indicates that the xenologous amniotic membrane can be useful as a tectonic graft in the repair of full-thickness lesions of the cornea of dogs.